Diagnosis of Benign and Malignant Liver Lesions

A focal lesion of the liver requires an immediate diagnostic work-up to determine its potential malignancy when detected by abdominal ultrasound. The distinction between either random findings by ultrasound or a past history of malignancy or known chronic liver disease including cirrhosis is of major clinical importance. Another important aspect for further work-up resembles the ultrasonic appearance of the liver lesion which can be subdivided into echo-free, hypoechoic or echogenic hepatic lesions. The two presently most important diagnostic procedures include magnetic resonance tomography and computed tomography. However, histology is often required to distinguish benign from malignant lesions by puncture either guided by ultrasound, magnetic resonance and computed tomography or endoscopic techniques. The close collaboration between general practitioners, hepatologists and interventional radiologists is necessary to obtain a rational approach to patients with focal liver lesions.

Source: Deutsches Ärzteblatt 98, Heft 47 vom 23.11.01, Seite A-3120